Two CIA officers were killed Sunday in a vehicle crash in Mexico's Chihuahua state while returning from an operation targeting drug laboratories, according to reports.

The crash occurred after the Americans participated in a Mexican armed forces-led operation to dismantle drug labs in the region. Two Mexican officials also died in the incident.

According to one report, the vehicle skidded off a ravine and exploded during the crash. The identities of the CIA officers have not been released.

The operation was described as targeting what may have been among the largest drug laboratories ever discovered in the region. Chihuahua state, which borders Texas and New Mexico, has been a key area for drug trafficking operations.

The incident highlights ongoing cooperation between U.S. and Mexican authorities in combating drug trafficking organizations operating along the border region. Further details about the specific operation and crash circumstances were not immediately available.