A cruise ship that experienced a deadly hantavirus outbreak arrived Monday morning in Rotterdam, Netherlands, concluding a seven-week journey that saw 11 passengers contract the rare virus and three deaths.

The MV Hondius, operated by Dutch company Oceanwide Expeditions, spent its final six days sailing from the Canary Islands with 25 crew members and two medical personnel aboard. All remaining passengers had been evacuated earlier at the Canary Islands, where they were escorted off by personnel in protective gear before boarding flights to more than 20 countries for quarantine.

The outbreak included nine confirmed cases and two additional suspected cases. Among the fatalities was a Dutch couple whom health officials believe may have been the first to contract the virus during a road trip through Argentina and Chile before boarding the ship in Ushuaia, Argentina's main Antarctic cruise hub. The Public Health Agency of Canada confirmed Sunday that one of four Canadians in isolation had tested positive for the virus.

Ushuaia, which bills itself as the "end of the world" and serves as the departure point for 90% of Antarctic cruises, now faces concerns about tourism impacts. Local officials and travel operators report cruise cancellations for the upcoming season, though authorities maintain there is no evidence the outbreak originated in their city. Argentina's Health Ministry is investigating the source but has not ruled out any destination visited by the Dutch couple during their monthslong South American trip.

The ship will undergo decontamination according to Dutch public health guidelines before being allowed to sail again. Crew members unable to return home will be quarantined in the Netherlands, joining two dozen passengers and crew already in isolation there. Eighteen Americans are under observation at specialized U.S. healthcare facilities.

France's Pasteur Institute said Saturday it had sequenced the Andes virus strain found in a French passenger and determined it matched known South American variants, with no evidence of increased transmissibility. This marks the first known hantavirus outbreak aboard a cruise ship, though Oceanwide Expeditions said it does not foresee operational changes and has an Arctic cruise scheduled to depart Iceland on May 29.